Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.80 |
| ▸ | LMNA | P02545 | 4/20 | 0.80 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.80 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.80 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.80 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | RAB9A | P51151 | 3/20 | 0.78 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.74 |
| ▸ | RAD52 | P43351 | 1/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15917496 | 1.00 | MAPT (0.80) | MAPTKMT2ALMNANPSR1DUSP3 | |
| SCHEMBL12443119 | 0.89 | MAPT (1.00) | MAPTKMT2ALMNANPSR1DUSP3 | |
| SCHEMBL28512241 | 0.86 | MAPT (0.84) | MAPTKMT2ALMNANPSR1DUSP3 | |
| SCHEMBL14581351 | 0.86 | MAPT (0.67) | MAPTKMT2ALMNANPSR1DUSP3 | |
| SCHEMBL27916039 | 0.86 | MAPT (0.73) | MAPTKMT2ALMNANPSR1DUSP3 | |
| SCHEMBL31005085 | 0.85 | IKBKB (0.73) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL8767795 | 0.84 | HDAC3 (0.72) | MAPTKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL28510033 | 0.83 | NOX4 (0.79) | MAPTKMT2ALMNANPSR1DUSP3 | |
| SCHEMBL8298517 | 0.83 | NOX4 (0.79) | MAPTKMT2ALMNANPSR1DUSP3 | |
| SCHEMBL13401672 | 0.83 | POLB (0.69) | MAPTKMT2ALMNANPSR1DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221429-A1 | HETEROCYCLIC SCHIFF'S BASES AS NOVEL AND NEW ANTIGLYCATION AGENTS | AL-RESAYES SAUD IBRAHIM (SA) | 2014-08-07 | — | — | US | disclosed |