Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 10/20 | 0.40 |
| ▸ | CNR2 | P34972 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919342 | 0.82 | CNR1 (0.49) | KMT2ACNR1CNR2 | |
| SCHEMBL6923152 | 0.80 | NOTUM (0.55) | KMT2ACNR1CNR2LMNANOTUM | |
| SCHEMBL23245606 | 0.72 | NOTUM (0.53) | KMT2ALMNANOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL23382307 | 0.72 | NOTUM (0.72) | KMT2ALMNANOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL28017573 | 0.71 | MAPT (0.51) | LMNAALDH1A1SMN1; SMN2GAA | |
| SCHEMBL17949738 | 0.70 | KMT2A (0.57) | KMT2ACNR1CNR2LMNANOTUM | |
| SCHEMBL28138493 | 0.68 | KMT2A (0.47) | KMT2ASMN1; SMN2 | |
| SCHEMBL23524483 | 0.67 | USP14 (0.65) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL6921620 | 0.66 | USP14 (0.63) | CNR1CNR2NOTUMALDH1A1SMN1; SMN2 | |
| SCHEMBL28138491 | 0.65 | HTT (0.65) | KMT2AALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116228-A1 | USP14 INHIBITORS FOR TREATING OR PREVENTING VIRAL INFECTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-07-31 | — | — | WO | disclosed |