Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.47 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919343 | 0.82 | KMT2A (0.43) | CNR1KMT2ACNR2 | |
| SCHEMBL6923383 | 0.80 | SMN1; SMN2 (0.63) | CNR1BLMKMT2ATAS1R3TAS1R1 | |
| SCHEMBL23382307 | 0.72 | NOTUM (0.72) | KMT2ARAB9ANPC1 | |
| SCHEMBL23245606 | 0.72 | NOTUM (0.53) | KMT2ARAB9ANPC1POLB | |
| SCHEMBL28017573 | 0.72 | MAPT (0.51) | RAB9ANPC1POLB | |
| SCHEMBL17949737 | 0.69 | RAB9A (0.65) | CNR1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL6699399 | 0.69 | CNR1 (0.85) | CNR1CNR2 | |
| SCHEMBL6923380 | 0.68 | SMN1; SMN2 (0.78) | CNR1KMT2ARAB9ANPC1CNR2 | |
| SCHEMBL1518457 | 0.67 | ALDH1A1 (0.61) | TAS1R3TAS1R1TAS1R2RAB9ANPC1 | |
| SCHEMBL19749162 | 0.67 | SMN1; SMN2 (0.61) | CNR1KMT2ARAB9ANPC1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116228-A1 | USP14 INHIBITORS FOR TREATING OR PREVENTING VIRAL INFECTIONS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-07-31 | — | — | WO | disclosed |