Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919652 | 0.93 | LMNA (0.36) | RAD52UBE2NMEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL17313777 | 0.92 | LMNA (0.36) | RAD52UBE2NMEN1KMT2AMAPT | |
| SCHEMBL17327547 | 0.91 | POLB (0.33) | RAD52UBE2NMEN1KMT2AMAPT | |
| SCHEMBL15919724 | 0.86 | ESR1 (0.33) | ESR1ESR2DHODHMAPT | |
| SCHEMBL15919298 | 0.81 | TACR3 (0.36) | RAD52UBE2NDHODHMAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL17313841 | 0.81 | TACR3 (0.35) | RAD52UBE2NDHODHMAPTMAPK1 | |
| SCHEMBL15919401 | 0.81 | TACR3 (0.38) | MEN1KMT2AMAPTLMNATSHR | |
| SCHEMBL17327500 | 0.80 | TACR3 (0.34) | RAD52UBE2NDHODHMEN1KMT2A | |
| SCHEMBL15919623 | 0.79 | CA2 (0.42) | MAPTLMNATSHR | |
| SCHEMBL15919475 | 0.79 | EGLN2 (0.38) | MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |