Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919860 | 0.87 | ALDH1A1 (0.68) | ALDH1A1KMT2APKMMEN1MAPT | |
| SCHEMBL10515849 | 0.84 | SETD7 (0.59) | ALDH1A1KMT2APKMCYP1A2CYP2C19 | |
| SCHEMBL15919864 | 0.84 | ALDH1A1 (0.64) | ALDH1A1KMT2APKMMEN1MAPT | |
| SCHEMBL15919855 | 0.84 | NPY2R (0.59) | ALDH1A1KMT2APKMMEN1GLA | |
| SCHEMBL14119792 | 0.81 | ALDH1A1 (0.82) | ALDH1A1KMT2APKMCYP1A2CYP2C19 | |
| SCHEMBL15423956 | 0.79 | ALDH1A1 (0.67) | ALDH1A1KMT2APKMCYP1A2CYP2C19 | |
| SCHEMBL11179944 | 0.78 | ALDH1A1 (0.96) | ALDH1A1KMT2APKMCYP1A2CYP2C19 | |
| SCHEMBL1651693 | 0.76 | ALDH1A1 (1.00) | ALDH1A1KMT2APKMCYP1A2CYP2C19 | |
| SCHEMBL13902470 | 0.73 | ALDH1A1 (0.70) | ALDH1A1KMT2APKMCYP1A2CYP2C19 | |
| SCHEMBL29582002 | 0.73 | KMT2A (0.69) | ALDH1A1KMT2APKMCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |