Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119792 | 0.87 | ALDH1A1 (0.82) | KMT2AALDH1A1CYP1A2MEN1GLA | |
| SCHEMBL11179944 | 0.83 | ALDH1A1 (0.96) | KMT2AALDH1A1CYP1A2MEN1GLA | |
| SCHEMBL16649940 | 0.83 | RAB9A (0.71) | KMT2AALDH1A1MEN1CYP2C19PKM | |
| SCHEMBL6224072 | 0.83 | TDP1 (0.71) | KMT2AALDH1A1CYP1A2MEN1CYP2C19 | |
| SCHEMBL1651693 | 0.81 | ALDH1A1 (1.00) | KMT2AALDH1A1CYP1A2MEN1GLA | |
| SCHEMBL656655 | 0.79 | POLB (0.97) | ALDH1A1CYP1A2GLACYP2C19MAPT | |
| SCHEMBL19380432 | 0.79 | MAPT (0.97) | KMT2AALDH1A1CYP1A2MEN1GLA | |
| SCHEMBL6803851 | 0.79 | POLB (0.63) | KMT2AALDH1A1CYP1A2MEN1GLA | |
| SCHEMBL13902470 | 0.79 | ALDH1A1 (0.70) | KMT2AALDH1A1CYP1A2MEN1GLA | |
| SCHEMBL7504156 | 0.77 | POLB (0.93) | ALDH1A1CYP1A2GLACYP2C19MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319303-B2 | Compound used as autophagy regulator, and preparation method therefor and uses thereof | Wigen Biomedicine Technology (shanghai) Co., Ltd. (CN) | 2022-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11319303-B2 | Compound used as autophagy regulator, and preparation method therefor and uses thereof | ATG7, SQSTM1, BECN1 | KMT2A 3378/4885ALDH1A1 4264/4885CYP1A2 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.