SCHEMBL1592016

SCHEMBL1592016

C=CC(=O)NCC(CCCCCC)NC(=O)C=C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC20 Q5W0Z9 2/20 0.56
ZDHHC2 Q9UIJ5 2/20 0.56
TGM2 P21980 1/20 0.39
TSHR P16473 2/20 0.39
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
FAAH O00519 2/20 0.38
PLA2G2C Q5R387 3/20 0.38
MAPK1 P28482 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
PLA2G2A P14555 1/20 0.36
GPR84 Q9NQS5 3/20 0.36
FFAR1 O14842 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1591997 0.98 ZDHHC20 (0.53) ZDHHC20ZDHHC2TGM2TSHRLCK
SCHEMBL1592568 0.94 ZDHHC20 (0.50) ZDHHC20ZDHHC2TGM2TSHRCNR1
SCHEMBL11512292 0.92 TSHR (0.43) ZDHHC20ZDHHC2TGM2TSHRMAPK1
SCHEMBL1412204 0.89 ZDHHC20 (0.55) ZDHHC20ZDHHC2TSHRLCKPPARD
SCHEMBL18557469 0.89 ZDHHC20 (0.55) ZDHHC20ZDHHC2TSHRLCKPPARD
SCHEMBL9314528 0.87 ZDHHC20 (0.53) ZDHHC20ZDHHC2TSHRLCKPPARD
SCHEMBL1592021 0.87 TAS1R3 (0.46) ZDHHC20ZDHHC2TGM2TSHRMAPK1
SCHEMBL12723739 0.86 ZDHHC20 (0.53) ZDHHC20ZDHHC2TGM2TSHRMAPK1
SCHEMBL6514878 0.85 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRLCKPPARD
SCHEMBL9314536 0.85 ZDHHC20 (0.51) ZDHHC20ZDHHC2TSHRLCKPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299191-B2 Shape memory polymers and process for preparing GEORGIA TECH RESEARCH CORP. (US) 2012-10-30 US disclosed
EP-2491082-A1 SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING Georgia Tech Research Corporation (US) 2012-08-29 EP disclosed
US-20110092652-A1 SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING GEORGIA TECH RESEARCH CORPORATION 2011-04-21 US disclosed