Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.81 |
| ▸ | SLC6A4 | P31645 | 13/20 | 0.81 |
| ▸ | OPRM1 | P35372 | 12/20 | 0.81 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.81 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.81 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.81 |
| ▸ | HTR3A | P46098 | 2/20 | 0.56 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| (R,R)-Tramadol SCHEMBL7464 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL12831358 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL6543836 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL1593740 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL11984200 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL5318670 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL3265792 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL730723 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL57495 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 | |
| (R,R)-Tramadol SCHEMBL14579837 | 0.90 | SLC6A2 (1.00) | SLC6A2SLC6A4OPRM1OPRD1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014115098-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND INFLAMMATION | KANDULA MAHESH (IN) | 2014-07-31 | — | — | WO | disclosed |