SCHEMBL15922387

SCHEMBL15922387

NC1(c2ccccc2)C2CC3CC(C2)CC1C3

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.49
GRIN2D O15399 1/20 0.47
GRIN3B O60391 1/20 0.47
GRIN1 Q05586 1/20 0.47
GRIN2A Q12879 1/20 0.47
GRIN2B Q13224 1/20 0.47
GRIN2C Q14957 1/20 0.47
GRIN3A Q8TCU5 1/20 0.47
MAOB P27338 9/20 0.39
MAOA P21397 8/20 0.39
KDM1A O60341 5/20 0.39
PNMT P11086 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15922645 1.00 HSD11B1 (0.49) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1557921 0.77 HSD11B1 (0.43) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1353430 0.77 HSD11B1 (0.52) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6896759 0.74 HSD11B1 (0.53) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL26828423 0.74 HSD11B1 (0.49) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6897711 0.74 HSD11B1 (0.62) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4846118 0.74 GRIN2D (0.47) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
Hydrochloric Acid SCHEMBL6894594 0.72 HSD11B1 (0.60) HSD11B1MAOBMAOA
SCHEMBL6680933 0.71 HSD11B1 (0.58) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL24549947 0.70 HSD11B1 (0.41) HSD11B1GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023210472-A1 RESIST COMPOSITION AND RESIST PATTERN FORMING METHOD 東京応化工業株式会社 2023-11-02 WO disclosed
US-9840465-B2 Antiviral compounds UNIV BRIGHAM YOUNG (US) 2017-12-12 US disclosed
US-9840465-B2 Antiviral compounds UNIV BRIGHAM YOUNG (US) 2017-12-12 US disclosed
US-20150368196-A1 ANTIVIRAL COMPOUNDS UNIV BRIGHAM YOUNG (US) 2015-12-24 US disclosed
US-20150368196-A1 ANTIVIRAL COMPOUNDS UNIV BRIGHAM YOUNG (US) 2015-12-24 US disclosed
EP-2950789-A2 ANTIVIRAL COMPOUNDS Brigham Young University (US) 2015-12-09 EP disclosed
WO-2014121170-A2 ANTIVIRAL COMPOUNDS BRIGHAM YOUNG UNIVERSITY (US) 2014-08-07 WO disclosed
WO-2014121170-A2 ANTIVIRAL COMPOUNDS BRIGHAM YOUNG UNIVERSITY (US) 2014-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150368196-A1 ANTIVIRAL COMPOUNDS ACE, ADA, MAVS HSD11B1 1386/4885GRIN2D 4607/4885GRIN3B 3613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.