SCHEMBL1592260

SCHEMBL1592260

C=CC(=O)OC(CCOC(=O)C(=C)C)C(C)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 10/20 0.41
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
ALDH1A1 P00352 5/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 2/20 0.31
POLB P06746 1/20 0.31
APEX1 P27695 1/20 0.31
HTT P42858 1/20 0.31
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL27677371 0.87 HTT (0.36) TSHRTHRBALOX15ALDH1A1TP53
SCHEMBL1405779 0.86 TSHR (0.47) TSHRTHRBHPGDALOX15ALDH1A1
SCHEMBL27543909 0.83 THRB (0.36) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL25309314 0.83 THRB (0.42) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL27847758 0.83 TSHR (0.44) TSHRTHRBHPGDALOX15ALDH1A1
SCHEMBL28331804 0.81 THRB (0.43) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL8528315 0.80 TSHR (0.44) TSHRTHRBHPGDALOX15ALDH1A1
SCHEMBL9157326 0.80 THRB (0.42) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL28201091 0.79 TSHR (0.38) TSHRTHRBHPGDALDH1A1TP53
SCHEMBL27654272 0.79 THRB (0.41) TSHRTHRBHPGDALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2328719-B1 ABRASIVE MATERIAL PRODUCT, ITS PRODUCTION METHOD AND USE METHOD 3M INNOVATIVE PROPERTIES CO (US) 2021-02-24 EP disclosed
US-9919406-B2 Abrasive material product, its production method and use method 3M INNOVATIVE PROPERTIES COMPANY (US) 2018-03-20 US disclosed
CN-102123830-B Abrasive material product, its production method and use method 3M INNOVATIVE PROPERTIES CO 2015-03-18 CN disclosed
CN-102123830-A Abrasive material product, its production method and use method 3M INNOVATIVE PROPERTIES CO 2011-07-13 CN disclosed
EP-2328719-A2 ABRASIVE MATERIAL PRODUCT, ITS PRODUCTION METHOD AND USE METHOD 3M Innovative Properties Company (US) 2011-06-08 EP disclosed
US-20110092137-A1 ABRASIVE MATERIAL PRODUCT, ITS PRODUCTION METHOD AND USE METHOD 3M INNOVATIVE PROPERTIES COMPANY 2011-04-21 US disclosed
WO-2010011801-A2 ABRASIVE MATERIAL PRODUCT, ITS PRODUCTION METHOD AND USE METHOD 3M INNOVATIVE PROPERTIES COMPANY (US) 2010-01-28 WO disclosed
CN-100334171-C Water printing ink KAO CORP (JP) 2007-08-29 CN disclosed
CN-1428382-A Water printing ink KAO CORP (JP) 2003-07-09 CN disclosed