Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.83 |
| ▸ | TCF4 | P15884 | 2/20 | 0.83 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.83 |
| ▸ | TCF7 | P36402 | 2/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CLPP | Q16740 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 17/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15647478 | 1.00 | CTNNB1 (0.83) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL15648154 | 1.00 | CTNNB1 (0.83) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL1592536 | 0.94 | CTNNB1 (0.75) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL15309358 | 0.94 | CTNNB1 (0.75) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL15476709 | 0.93 | CTNNB1 (0.87) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL23668060 | 0.92 | CTNNB1 (0.80) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL15477009 | 0.92 | CTNNB1 (0.80) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL1591853 | 0.92 | CTNNB1 (0.71) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL15309446 | 0.92 | CTNNB1 (0.71) | CTNNB1TCF4CREBBPTCF7BCL9 | |
| SCHEMBL1591993 | 0.92 | CTNNB1 (0.79) | CTNNB1TCF4CREBBPTCF7BCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210379021-A1 | METHOD FOR PREPARING AND DELIVERING BISANTRENE FORMULATIONS | RACE ONCOLOGY LTD (AU) | 2021-12-09 | — | — | US | claimed |
| CN-113365610-A | Methods of making and delivering bisantrene formulations | 现代化制药公司 | 2021-09-07 | — | — | CN | claimed |
| US-20160318938-A1 | CRYSTALS (2) OF PYRAZINO[2,1-c][1,2,4]TRIAZINE COMPOUND | PRISM PHARMA CO., LTD. (JP) | 2016-11-03 | — | — | US | claimed |
| EP-3088402-A1 | CRYSTALS (2) OF PYRAZINO[2,1-c][1,2,4]TRIAZINE COMPOUND | PRISM Pharma Co., Ltd. (JP) | 2016-11-02 | — | — | EP | claimed |
| US-20160263131-A1 | TREATMENT OF HEPATIC FIBROSIS USING AN INHIBITOR OF CBP/CATENIN | KOUJI HIROYUKI (JP) | 2016-09-15 | — | — | US | claimed |
| US-20160244453-A1 | TREATMENT OF VIRAL AND INFECTIOUS DISEASES USING AN INHIBITOR OF CBP/CATENIN | PRISM PHARMA CO., LTD. (JP) | 2016-08-25 | — | — | US | claimed |
| EP-3057590-A2 | TREATMENT OF HEPATIC FIBROSIS USING AN INHIBITOR OF CBP/CATENIN | Kouji, Hiroyuki (JP) | 2016-08-24 | — | — | EP | claimed |
| US-20160215007-A1 | METHOD OF PRODUCING PYRAZINO[2,1-C][1,2,4]TRIAZINE COMPOUND | PRISM PHARMA CO., LTD. (JP) | 2016-07-28 | — | — | US | claimed |
| EP-3045464-A1 | METHOD OF PRODUCING PYRAZINO[2,1-C][1,2,4]TRIAZINE COMPOUND | PRISM Pharma Co., Ltd. (JP) | 2016-07-20 | — | — | EP | claimed |
| US-20160166577-A1 | TREATMENT OF PULMONARY FIBROSIS USING AN INHIBITOR OF CBP/CATENIN | PRISM PHARMA CO., LTD. (JP) | 2016-06-16 | — | — | US | claimed |
| EP-2303887-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORP (JP) | 2015-08-05 | — | — | EP | claimed |
| WO-2015056104-A2 | TREATMENT OF HEPATIC FIBROSIS USING AN INHIBITOR OF CBP/CATENIN | KOUJI HIROYUKI (JP) | 2015-04-23 | — | — | WO | claimed |
| WO-2014061823-A1 | METHOD FOR TREATING TYPE I AND TYPE II DIABETES | KOUJI HIROYUKI (JP) | 2014-04-24 | — | — | WO | claimed |
| WO-2014061827-A1 | TREATMENT OF PULMONARY FIBROSIS USING AN INHIBITOR OF CBP/CATENIN | KOUJI HIROYUKI (JP) | 2014-04-24 | — | — | WO | claimed |
| WO-2014061824-A1 | METHODS FOR TREATING EYE DISORDERS | KOUJI HIROYUKI (JP) | 2014-04-24 | — | — | WO | claimed |
| WO-2014061828-A1 | TREATMENT OF SCLERODERMA USING AN INHIBITOR OF CBP/CATENIN | KOUJI HIROYUKI (JP) | 2014-04-24 | — | — | WO | claimed |
| EP-2650295-A1 | Alpha helix mimetics and methods relating thereto | Prism Biolab Corporation (JP) | 2013-10-16 | — | — | EP | claimed |
| US-20130267482-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM PHARMA CO., LTD. (JP) | 2013-10-10 | — | — | US | claimed |
| US-8455488-B2 | Alpha helix mimetics and methods relating thereto | PRISM BIOLAB CORPORATION (JP) | 2013-06-04 | — | — | US | claimed |
| US-20110092459-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2011-04-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267482-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | COL1A1, PLOD3, THPO | CTNNB1 416/4885TCF4 572/4885CREBBP 569/4885 |
| US-20160215007-A1 | METHOD OF PRODUCING PYRAZINO[2,1-C][1,2,4]TRIAZINE COMPOUND | TYMP, DTYMK, MTAP | CTNNB1 831/4885TCF4 494/4885CREBBP 1197/4885 |
| US-20160263131-A1 | TREATMENT OF HEPATIC FIBROSIS USING AN INHIBITOR OF CBP/CATENIN | CTNNBL1, CTNNB1, CREBBP | CTNNB1 2/4885TCF4 68/4885CREBBP 3/4885 |
| US-20210379021-A1 | METHOD FOR PREPARING AND DELIVERING BISANTRENE FORMULATIONS | CYP3A43, CYP1A1, UGT1A3 | CTNNB1 1181/4885TCF4 3381/4885CREBBP 4846/4885 |
| US-20160166577-A1 | TREATMENT OF PULMONARY FIBROSIS USING AN INHIBITOR OF CBP/CATENIN | CTNNB1, CTNNBL1, CTNNA1 | CTNNB1 1/4885TCF4 39/4885CREBBP 6/4885 |
| US-20110092459-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | COL1A1, PLOD3, THPO | CTNNB1 416/4885TCF4 572/4885CREBBP 569/4885 |
| US-20160244453-A1 | TREATMENT OF VIRAL AND INFECTIOUS DISEASES USING AN INHIBITOR OF CBP/CATENIN | CTNNB1, CTNNBL1, CTNNA1 | CTNNB1 1/4885TCF4 48/4885CREBBP 6/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.