Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143530 | 0.92 | TP53 (0.41) | TP53SMN1; SMN2MAPK1ATMGAA | |
| SCHEMBL455945 | 0.88 | TP53 (0.36) | TP53SMN1; SMN2MAPK1ATMGAA | |
| SCHEMBL15922741 | 0.88 | TP53 (0.39) | TP53SMN1; SMN2MAPK1ATMGAA | |
| SCHEMBL11355878 | 0.88 | HSD11B1 (0.41) | TP53SMN1; SMN2MAPK1ATMLMNA | |
| SCHEMBL19073248 | 0.87 | TP53 (0.36) | TP53SMN1; SMN2MAPK1ATMGAA | |
| SCHEMBL18177915 | 0.87 | HTT (0.47) | TP53SMN1; SMN2MAPK1ATMGAA | |
| Hydrochloric Acid SCHEMBL1697515 | 0.86 | SMN1; SMN2 (0.38) | TP53SMN1; SMN2MAPK1ATMGAA | |
| SCHEMBL15922928 | 0.86 | HSD11B1 (0.43) | TP53SMN1; SMN2GAATSHRPOLB | |
| SCHEMBL10436532 | 0.86 | HSD11B1 (0.43) | TP53SMN1; SMN2GAATSHRPOLB | |
| SCHEMBL1150375 | 0.82 | KDM4E (0.48) | TP53SMN1; SMN2MAPK1TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9840465-B2 | Antiviral compounds | UNIV BRIGHAM YOUNG (US) | 2017-12-12 | — | — | US | disclosed |
| US-20150368196-A1 | ANTIVIRAL COMPOUNDS | UNIV BRIGHAM YOUNG (US) | 2015-12-24 | — | — | US | disclosed |
| EP-2950789-A2 | ANTIVIRAL COMPOUNDS | Brigham Young University (US) | 2015-12-09 | — | — | EP | disclosed |
| CN-104428331-A | Active energy ray-polymerizable resin composition and laminate obtained using resin composition | TOYO INK SC HOLDINGS CO LTD | 2015-03-18 | — | — | CN | disclosed |
| WO-2014121170-A2 | ANTIVIRAL COMPOUNDS | BRIGHAM YOUNG UNIVERSITY (US) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368196-A1 | ANTIVIRAL COMPOUNDS | ACE, ADA, MAVS | TP53 2064/4885SMN1; SMN2 4527/4885MAPK1 3804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.