⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27841296 | 0.90 | L3MBTL1 (0.32) | — | |
| SCHEMBL15922795 | 0.88 | L3MBTL1 (0.36) | — | |
| SCHEMBL1450944 | 0.85 | — | — | |
| SCHEMBL28298179 | 0.85 | — | — | |
| SCHEMBL4290579 | 0.75 | — | — | |
| SCHEMBL1461077 | 0.66 | — | — | |
| SCHEMBL10597746 | 0.63 | — | — | |
| SCHEMBL10597753 | 0.63 | — | — | |
| SCHEMBL3946060 | 0.63 | CCR5 (0.30) | — | |
| SCHEMBL6338776 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328126-B2 | Norbornenylhydrocarbylene dihydrocarbylboranes and methods of making the same | PROMERUS, LLC (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150353582-A1 | NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME | PROMERUS, LLC (US) | 2015-12-10 | — | — | US | disclosed |
| WO-2014121008-A1 | NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME | PROMERUS, LLC (US) | 2014-08-07 | — | — | WO | disclosed |