⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1191487 | 0.71 | MEN1 (0.40) | — | |
| SCHEMBL642226 | 0.69 | — | — | |
| SCHEMBL1205563 | 0.69 | — | — | |
| SCHEMBL21401230 | 0.67 | — | — | |
| SCHEMBL7052729 | 0.67 | — | — | |
| SCHEMBL15923447 | 0.67 | — | — | |
| SCHEMBL11591369 | 0.67 | — | — | |
| SCHEMBL1397907 | 0.67 | — | — | |
| SCHEMBL2465330 | 0.67 | — | — | |
| SCHEMBL446051 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020016830-A1 | LOW TEMPERATURE STABLE FORMULATIONS OF UREASE INHIBITOR-CONTAINING COMPOSITIONS | KOCH AGRONOMIC SERVICES, LLC (US) | 2020-01-23 | — | — | WO | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| EP-0370902-B1 | USE OF CHROMANE DERIVATIVES IN THE PREPARATION OF A MEDICAMENT FOR THE TREATMENT OF DEPRESSIVE CONDITIONS | ELF SANOFI (FR) | 1992-08-26 | — | — | EP | claimed |
| US-5043352-A | Chroman derivatives for the treatment of depressive states | SANOFI (FR) | 1991-08-27 | — | — | US | claimed |
| EP-4125885-B1 | USE OF A THIENOPYRIDONE DERIVATIVE IN THE TREATMENT OF DIABETIC NEPHROPATHY | POXEL (FR) | 2024-12-25 | — | — | EP | disclosed |
| EP-4125885-C0 | USE OF A THIENOPYRIDONE DERIVATIVE IN THE TREATMENT OF DIABETIC NEPHROPATHY | POXEL (FR) | 2024-12-25 | — | — | EP | disclosed |
| EP-3393650-B1 | ELECTROCHEMICAL REACTOR TO CONTROL THE PH IN MINIATURISED DIMENSIONS | LUXEMBOURG INST SCIENCE & TECH LIST (LU) | 2024-08-07 | — | — | EP | disclosed |
| CN-117597327-A | Pharmaceutical preparation | 第一波动生物制药股份有限公司 | 2024-02-23 | — | — | CN | disclosed |
| EP-4125885-A1 | USE OF A THIENOPYRIDONE DERIVATIVE IN THE TREATMENT OF DIABETIC NEPHROPATHY | Poxel (FR) | 2023-02-08 | — | — | EP | disclosed |
| EP-4125886-A1 | USE OF A THIENOPYRIDONE DERIVATIVE IN THE TREATMENT OF ADRENOLEUKODYSTROPHY OR ADRENOMYELONEUROPATHY | Poxel (FR) | 2023-02-08 | — | — | EP | disclosed |
| WO-2020016830-A1 | LOW TEMPERATURE STABLE FORMULATIONS OF UREASE INHIBITOR-CONTAINING COMPOSITIONS | KOCH AGRONOMIC SERVICES, LLC (US) | 2020-01-23 | — | — | WO | disclosed |
| EP-2343069-B1 | Heterocyclic aspartyl protease inhibitors | MERCK SHARP & DOHME (US) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014151784-A1 | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PARASITIC DISEASES | IRM LLC (BM) | 2014-09-25 | — | — | WO | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5043352-A | Chroman derivatives for the treatment of depressive states | SANOFI (FR) | 1991-08-27 | — | — | US | disclosed |
| US-5043352-A | Chroman derivatives for the treatment of depressive states | SANOFI (FR) | 1991-08-27 | — | — | US | disclosed |
| EP-0370902-A2 | Use of chromane derivatives in the preparation of a medicament for the treatment of depressive conditions | ELF SANOFI (FR) | 1990-05-30 | — | — | EP | disclosed |