SCHEMBL1592363

SCHEMBL1592363

C=CC(=O)OC1C2CC1C2

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.33
ALDH1A1 P00352 4/20 0.33
TP53 P04637 3/20 0.33
HIF1A Q16665 3/20 0.33
CYP3A4 P08684 2/20 0.33
HSD11B1 P28845 1/20 0.33
HSD17B10 Q99714 1/20 0.33
EPHX1 P07099 1/20 0.32
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14593964 0.92 CYP2C9 (0.31) HSD11B1
SCHEMBL1592345 0.91 ATM (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL333419 0.89 HSD11B1 (0.46) TSHRALDH1A1CYP3A4HSD11B1HSD17B10
SCHEMBL23494177 0.87 EPHX1 (0.32) ALDH1A1HSD11B1EPHX1
SCHEMBL18793062 0.87 ALDH1A1 (0.34) TSHRALDH1A1
SCHEMBL13531315 0.86 TSHR (0.33) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL19919330 0.84
SCHEMBL18973585 0.84 HSD11B1 (0.35) HSD11B1EPHX1
SCHEMBL15827344 0.83
SCHEMBL6536762 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8299191-B2 Shape memory polymers and process for preparing GEORGIA TECH RESEARCH CORP. (US) 2012-10-30 US claimed
US-20110092652-A1 SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING GEORGIA TECH RESEARCH CORPORATION 2011-04-21 US claimed
US-12186974-B2 Method of manufacturing a heat-shrink elastomeric element HALLIBURTON ENERGY SERVICES, INC. (US) 2025-01-07 US disclosed
US-20210323217-A1 METHOD OF MANUFACTURING A HEAT-SHRINK ELASTOMERIC ELEMENT HALLIBURTON ENERGY SERVICES, INC. 2021-10-21 US disclosed
US-11065807-B2 Method of manufacturing a heat-shrink elastomeric element THE UNIVERSITY OF TEXAS SYSTEM BOARD OF REGENTS (US) 2021-07-20 US disclosed
US-20190077070-A1 HEAT-SHRINK ELASTOMERIC ELEMENTS MADE FROM SHAPE MEMORY POLYMERS HALLIBURTON ENERGY SERVICES, INC. 2019-03-14 US disclosed
US-8299191-B2 Shape memory polymers and process for preparing GEORGIA TECH RESEARCH CORP. (US) 2012-10-30 US disclosed
US-20110092652-A1 SHAPE MEMORY POLYMERS AND PROCESS FOR PREPARING GEORGIA TECH RESEARCH CORPORATION 2011-04-21 US disclosed