SCHEMBL15924889

SCHEMBL15924889

CCC=C(C#N)C(=O)OCCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.46
DNM1 Q05193 2/20 0.43
TP53 P04637 2/20 0.43
CYP2C9 P11712 2/20 0.42
NAAA Q02083 1/20 0.42
HCAR2 Q8TDS4 2/20 0.41
RAD52 P43351 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CYP3A4 P08684 2/20 0.40
MEN1 O00255 1/20 0.40
LMNA P02545 1/20 0.40
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C19 P33261 1/20 0.40
KMT2A Q03164 1/20 0.40
EPHX1 P07099 1/20 0.40
ATM Q13315 1/20 0.39
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11147631 0.98 TSHR (0.49) TSHRDNM1TP53CYP2C9NAAA
SCHEMBL7737783 0.95 TP53 (0.46) TSHRDNM1TP53CYP2C9HCAR2
SCHEMBL7737784 0.95 TP53 (0.46) TSHRDNM1TP53CYP2C9HCAR2
SCHEMBL22502563 0.91 ZDHHC20 (0.39) TSHRDNM1TP53CYP2C9NAAA
SCHEMBL22502697 0.90 ZDHHC20 (0.41) TSHRDNM1TP53CYP2C9NAAA
SCHEMBL20472622 0.87 TSHR (0.47) TSHRDNM1TP53CYP2C9NAAA
SCHEMBL13703525 0.87 TSHR (0.47) TSHRDNM1TP53CYP2C9NAAA
SCHEMBL20472626 0.87 TSHR (0.47) TSHRDNM1TP53CYP2C9NAAA
SCHEMBL8000911 0.86 TSHR (0.53) TSHRDNM1TP53CYP2C9NAAA
SCHEMBL22502664 0.86 TP53 (0.40) TSHRDNM1TP53CYP2C9NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9657205-B2 Adhesive beads Dry, Carolyn (US) 2017-05-23 US claimed
US-20150361314-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2015-12-17 US claimed
EP-2951256-A1 ADHESIVE BEADS Dry, Carolyn M. (US) 2015-12-09 EP claimed
WO-2014121223-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2014-08-07 WO claimed
US-10011149-B2 Self-repairing inflatable articles DRY CAROLYN M (US) 2018-07-03 US disclosed
US-9694629-B1 Self-repairing inflatable articles incorporating an integrated self-repair system Dry, Carolyn (US) 2017-07-04 US disclosed
US-9683816-B2 Self-repairing armor Dry, Carolyn (US) 2017-06-20 US disclosed
US-9657205-B2 Adhesive beads Dry, Carolyn (US) 2017-05-23 US disclosed
US-20160195367-A1 SELF-REPAIRING ARMOR DRY CAROLYN (US) 2016-07-07 US disclosed
US-20150361314-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2015-12-17 US disclosed
EP-2951256-A1 ADHESIVE BEADS Dry, Carolyn M. (US) 2015-12-09 EP disclosed
US-20150056391-A1 SELF-REPAIRING INFLATABLE ARTICLES DRY CAROLYN M (US) 2015-02-26 US disclosed
US-8877309-B1 Self-repairing inflatable articles DRY CAROLYN M (US) 2014-11-04 US disclosed
WO-2014121223-A1 ADHESIVE BEADS DRY CAROLYN M (US) 2014-08-07 WO disclosed