SCHEMBL7737784

SCHEMBL7737784

CCC=C(C#N)C(=O)OCCCC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.46
ATM Q13315 1/20 0.44
CYP2C9 P11712 2/20 0.44
ALDH1A1 P00352 2/20 0.42
TSHR P16473 3/20 0.42
HPGD P15428 1/20 0.42
DNM1 Q05193 3/20 0.41
HCAR2 Q8TDS4 1/20 0.40
POLB P06746 2/20 0.38
MAPT P10636 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
CYP3A4 P08684 1/20 0.38
GAA P10253 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 1/20 0.38
PDCD1 Q15116 1/20 0.37
CD274 Q9NZQ7 1/20 0.37
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7737783 1.00 TP53 (0.46) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL15924889 0.95 TSHR (0.46) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL11147631 0.93 TSHR (0.49) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL22502664 0.91 TP53 (0.40) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL24755221 0.89 CYP2C9 (0.46) TP53CYP2C9ALDH1A1TSHRDNM1
SCHEMBL7745794 0.88 TP53 (0.45) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7745797 0.88 TP53 (0.45) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7737758 0.88 TP53 (0.45) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7737755 0.88 TP53 (0.45) TP53ATMCYP2C9ALDH1A1TSHR
SCHEMBL7743874 0.87 TP53 (0.49) TP53ATMCYP2C9ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN claimed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN claimed
EP-0824316-A4 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 2001-01-17 EP claimed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 US claimed
EP-0824316-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH Nielsen, Thor, B. (US) 1998-02-25 EP claimed
WO-1996034526-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 1996-11-07 WO claimed
US-11957793-B2 Nanoparticles SINTEF TTO AS (NO) 2024-04-16 US disclosed
EP-3840736-B1 NANOPARTICLES SINTEF TTO AS (NO) 2022-06-15 EP disclosed
US-20210236435-A1 Nanoparticles SINTEF TTO AS (NO) 2021-08-05 US disclosed
EP-3840736-A1 NANOPARTICLES Sintef TTO AS (NO) 2021-06-30 EP disclosed
WO-2020039081-A1 NANOPARTICLES SINTEF TTO AS (NO) 2020-02-27 WO disclosed
CN-110022860-A For treating the new drug delivery system of disease 斯特凡TTO有限公司 2019-07-16 CN disclosed
CN-103922964-B Alpha-cyanoacrylate butyl ester derivative and preparation method thereof GUANGZHOU BAIYUN MEDICAL ADHESIVE CO., LTD. (CN) 2016-03-02 CN disclosed
CN-103922964-A Alpha-butyl cyanoacrylate derivative and preparation method thereof GUANGZHOU BAIYUN MEDICAL ADHESIVE CO LTD 2014-07-16 CN disclosed
CN-102264852-A Adhesive composition 2011-11-30 CN disclosed
CN-101305040-A Binding agent, sealant and paint containing glass particle as filling material HENKEL AG & CO KGAA (DE) 2008-11-12 CN disclosed
CN-101305064-A Binding agent, sealant and paint containing glass particle as filling material HENKEL AG & CO KGAA (DE) 2008-11-12 CN disclosed
CN-1239653-C Cyanoacrylate compositions, reaction products, methods of preparation and uses thereof LOCTITE R & D LTD (IE) 2006-02-01 CN disclosed
CN-1487983-A Cyanoacrylate compositions curable to flexible polymeric materials ���̩��(R&D)���޹�˾ 2004-04-07 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210236435-A1 Nanoparticles CBR3, CBR1, AKR1C3 TP53 1690/4885ATM 3045/4885CYP2C9 308/4885
US-11957793-B2 Nanoparticles CBR3, CBR1, AKR1C3 TP53 1808/4885ATM 3228/4885CYP2C9 373/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.