Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925466 | 0.91 | CETP (0.49) | CETPARSMN1; SMN2APPRAB9A | |
| SCHEMBL15925487 | 0.89 | CETP (0.48) | CETPARSMN1; SMN2APPRAB9A | |
| SCHEMBL15925460 | 0.87 | AR (0.51) | CETPARSMN1; SMN2RAB9APPARG | |
| SCHEMBL10298676 | 0.86 | CETP (0.56) | CETPSMN1; SMN2APPRAB9AALDH1A1 | |
| SCHEMBL15925462 | 0.85 | SMN1; SMN2 (0.49) | CETPARSMN1; SMN2RAB9APPARG | |
| SCHEMBL10298347 | 0.84 | CETP (0.57) | CETPSMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL15925455 | 0.82 | AR (0.52) | CETPARSMN1; SMN2RAB9APPARG | |
| SCHEMBL15925461 | 0.81 | ALOX15 (0.52) | ARSMN1; SMN2RAB9APPARGPPARA | |
| SCHEMBL15925464 | 0.80 | SMN1; SMN2 (0.50) | CETPARSMN1; SMN2RAB9APPARG | |
| SCHEMBL15925468 | 0.79 | AR (0.44) | CETPARSMN1; SMN2RAB9APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796268-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |