Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.40 |
| ▸ | PIK3C3 | Q8NEB9 | 12/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.36 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925699 | 0.90 | CDC7 (0.43) | CDC7DBF4PIK3C3AAK1CYP3A4 | |
| SCHEMBL10288582 | 0.89 | CDC7 (0.39) | CDC7DBF4PIK3C3AAK1CYP3A4 | |
| SCHEMBL15925740 | 0.89 | CDC7 (0.40) | CDC7DBF4PIK3C3AAK1CYP3A4 | |
| SCHEMBL15925761 | 0.85 | CDC7 (0.41) | CDC7DBF4PIK3C3TGFBR1TGFBR2 | |
| SCHEMBL15925767 | 0.84 | CDC7 (0.39) | CDC7DBF4PIK3C3AAK1CYP3A4 | |
| SCHEMBL15925697 | 0.83 | CYP19A1 (0.33) | CDC7DBF4FFAR2 | |
| SCHEMBL15925763 | 0.82 | CDC7 (0.37) | CDC7DBF4PIK3C3AAK1CYP3A4 | |
| SCHEMBL15925755 | 0.80 | CDC7 (0.37) | CDC7DBF4PIK3C3AAK1CYP3A4 | |
| SCHEMBL15925774 | 0.80 | CDC7 (0.37) | CDC7DBF4PIK3C3AAK1CYP3A4 | |
| SCHEMBL954033 | 0.79 | CDC7 (0.46) | CDC7DBF4PIK3C3AAK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796271-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |