Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27422823 | 0.85 | TDP1 (0.38) | TDP1TSHR | |
| SCHEMBL14618765 | 0.83 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL21782825 | 0.83 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL23220490 | 0.83 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL14747616 | 0.83 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL23220483 | 0.83 | TDP1 (0.36) | TDP1TSHR | |
| SCHEMBL16716490 | 0.82 | TDP1 (0.32) | TDP1 | |
| SCHEMBL16316044 | 0.81 | TDP1 (0.35) | TDP1TSHR | |
| SCHEMBL16949344 | 0.80 | — | — | |
| SCHEMBL16270533 | 0.78 | TDP1 (0.36) | TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140370501-A1 | HYDROLASE ENZYME SUBSTRATES AND USES THEREOF | DIAZYME LABORATORIES, INC. | 2014-12-18 | — | — | US | disclosed |
| US-8795979-B2 | Hydrolase enzyme substrates and uses thereof | GENERAL ATOMICS (US) | 2014-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140370501-A1 | HYDROLASE ENZYME SUBSTRATES AND USES THEREOF | DNPH1, HDHD5, ENGASE | TDP1 434/4885TSHR 4420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.