Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.31 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15926318 | 0.94 | MAPK14 (0.32) | MAPK14MAPTEP300CREBBPKAT2A | |
| SCHEMBL1614666 | 0.90 | MAPT (0.33) | MAPT | |
| SCHEMBL1614735 | 0.89 | PLAT (0.33) | MAPK14MAPT | |
| SCHEMBL15909062 | 0.85 | NPC1 (0.38) | — | |
| SCHEMBL15926361 | 0.84 | HCAR2 (0.35) | MAPK14MAPTEP300CREBBPKAT2A | |
| SCHEMBL15926362 | 0.82 | AR (0.37) | — | |
| SCHEMBL15909005 | 0.79 | HDAC1 (0.40) | — | |
| SCHEMBL15926314 | 0.78 | KCNQ3 (0.36) | MAPT | |
| SCHEMBL1613466 | 0.78 | AR (0.40) | MAPT | |
| SCHEMBL1615018 | 0.77 | HCAR2 (0.35) | MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796285-B2 | Pyrazolo [1,5-a]-pyrimidones derivatives and pharmaceutical compositions and uses thereof | HEBEI MEDICAL UNIVERSITY (CN) | 2014-08-05 | — | — | US | disclosed |