Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | MAX | P61244 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | EP300 | Q09472 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
| ▸ | ARF6 | P62330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15926328 | 0.94 | MAPK14 (0.31) | MAPK14MAPTEP300CREBBPKAT2A | |
| SCHEMBL1614735 | 0.91 | PLAT (0.33) | MAPK14KCNQ3KCNQ2MYCMAX | |
| SCHEMBL1614666 | 0.91 | MAPT (0.33) | KCNQ3KCNQ2MYCMAXGHSR | |
| SCHEMBL15926361 | 0.90 | HCAR2 (0.35) | MAPK14KCNQ3KCNQ2KDM4EALDH1A1 | |
| SCHEMBL15926362 | 0.87 | AR (0.37) | KCNQ3KCNQ2GHSRKDM4EALDH1A1 | |
| SCHEMBL15909005 | 0.84 | HDAC1 (0.40) | KDM4EALDH1A1GAA | |
| SCHEMBL15926314 | 0.83 | KCNQ3 (0.36) | KCNQ3KCNQ2GAAMAPTARF6 | |
| SCHEMBL15926352 | 0.81 | MAPT (0.36) | KCNQ3KCNQ2MAPTARF6 | |
| SCHEMBL1615018 | 0.81 | HCAR2 (0.35) | MAPK14KCNQ3KCNQ2KDM4EALDH1A1 | |
| SCHEMBL1613466 | 0.80 | AR (0.40) | GHSRMAPTARF6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796285-B2 | Pyrazolo [1,5-a]-pyrimidones derivatives and pharmaceutical compositions and uses thereof | HEBEI MEDICAL UNIVERSITY (CN) | 2014-08-05 | — | — | US | disclosed |