Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 8/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 8/20 | 0.35 |
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | LGMN | Q99538 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15926416 | 0.84 | KDM4E (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL15925819 | 0.83 | MAPT (0.45) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13386268 | 0.81 | KMT2A (0.34) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13386335 | 0.80 | MAPT (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| Iodide SCHEMBL13386230 | 0.79 | MEN1 (0.36) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL15925818 | 0.79 | MAPT (0.42) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL17896427 | 0.79 | MAPT (0.42) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL16004720 | 0.78 | KDM4E (0.43) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13386392 | 0.78 | LGMN (0.44) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13386208 | 0.78 | ADRB1 (0.44) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796448-B1 | Compounds, compositions, and methods for treating Alzheimer's disease | PROSETTA ANTIVIRAL INC. (US) | 2014-08-05 | — | — | US | disclosed |