Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.59 |
| ▸ | CTSK | P43235 | 7/20 | 0.58 |
| ▸ | CTSL | P07711 | 7/20 | 0.55 |
| ▸ | CTSB | P07858 | 6/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14148283 | 1.00 | CAPN1 (0.59) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL5711394 | 0.90 | ITGB3 (0.54) | CTSLCTSBCTSS | |
| SCHEMBL7327426 | 0.84 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL27809377 | 0.84 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL9828791 | 0.84 | CAPN1 (0.78) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL6466337 | 0.84 | CTSK (0.60) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL25406813 | 0.83 | CTSK (0.77) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL20770085 | 0.83 | CTSK (0.77) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL8823918 | 0.83 | CTSK (0.77) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL4872585 | 0.83 | CTSK (0.77) | CAPN1CTSKCTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796202-B2 | Multi-valent poly-Ubl chain inhibitors and methods of use | CITY OF HOPE (US) | 2014-08-05 | — | — | US | disclosed |