Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLQ | O75417 | 1/20 | 0.40 |
| ▸ | ATF1 | P18846 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1559570 | 0.88 | TP53 (0.47) | TP53NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1593482 | 0.86 | TP53 (0.44) | TP53NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1560147 | 0.86 | TP53 (0.48) | TP53NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1559099 | 0.79 | TP53 (0.45) | TP53NPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1559543 | 0.78 | TP53 (0.42) | TP53NPC1RAB9AMAPTGRM5 | |
| SCHEMBL1560421 | 0.78 | TP53 (0.42) | TP53NPC1RAB9AMAPTGRM5 | |
| SCHEMBL1560195 | 0.76 | MAPT (0.45) | TP53NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL1558934 | 0.74 | NPC1 (0.41) | TP53NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL1560544 | 0.73 | ALOX5AP (0.39) | TP53NPC1RAB9AMAPT | |
| SCHEMBL1558980 | 0.73 | ALDH1A1 (0.43) | TP53SMN1; SMN2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092544-A1 | FUNGICIDAL PYRIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092544-A1 | FUNGICIDAL PYRIDINES | CBR3, CBR1, CYP8B1 | TP53 4508/4885NPC1 367/4885RAB9A 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.