Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558980 | 0.88 | ALDH1A1 (0.43) | TP53GAAPOLBALDH1A1KDM4E | |
| SCHEMBL1592745 | 0.86 | TP53 (0.54) | TP53ALDH1A1LMNASMN1; SMN2NPC1 | |
| SCHEMBL1558996 | 0.78 | ALDH1A1 (0.51) | GAAPOLBALDH1A1KDM4ELMNA | |
| SCHEMBL8364027 | 0.76 | TSHR (0.52) | GAAALDH1A1KDM4ELMNAHPGD | |
| SCHEMBL2648886 | 0.75 | GAA (0.59) | GAAPOLBALDH1A1KDM4ELMNA | |
| SCHEMBL1560421 | 0.74 | TP53 (0.42) | TP53NPC1RAB9AMAPT | |
| SCHEMBL1593482 | 0.73 | TP53 (0.44) | TP53ALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2649097 | 0.73 | ALDH1A1 (0.60) | TP53GAAPOLBALDH1A1KDM4E | |
| SCHEMBL1560195 | 0.72 | MAPT (0.45) | TP53ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5014336 | 0.72 | FOS (0.60) | TP53GAAPOLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092544-A1 | FUNGICIDAL PYRIDINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-04-21 | — | — | US | disclosed |
| EP-2303843-A2 | FUNGICIDAL PYRIDINES | E. I. du Pont de Nemours and Company (US) | 2011-04-06 | — | — | EP | disclosed |
| WO-2009158257-A2 | FUNGICIDAL PYRIDINES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092544-A1 | FUNGICIDAL PYRIDINES | CBR3, CBR1, CYP8B1 | TP53 4508/4885GAA 2584/4885POLB 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.