SCHEMBL15927508

SCHEMBL15927508

CC1(C)Cc2ccc(C(=O)CBr)cc2C1

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 11/20 0.47
PTPN1 P18031 6/20 0.46
GNG2 P59768 1/20 0.46
GNB1 P62873 1/20 0.46
CNR1 P21554 5/20 0.44
CNR2 P34972 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15927440 0.86 CNR1 (0.47) GNG2GNB1CNR1CNR2
SCHEMBL23753567 0.82 CNR1 (0.42) CNR1CNR2
SCHEMBL12619017 0.80 ALDH1A1 (0.53) CNR1CNR2
SCHEMBL15927500 0.78 PTPN1 (0.52) GSK3BPTPN1GNG2GNB1
SCHEMBL2224448 0.78 GNG2 (0.45) GSK3BPTPN1GNG2GNB1
SCHEMBL15106223 0.77 NPC1 (0.58) GSK3BPTPN1GNG2GNB1
SCHEMBL2223215 0.75 GNG2 (0.52) GSK3BPTPN1GNG2GNB1
SCHEMBL1182899 0.75 ALDH1A1 (0.61) GSK3BPTPN1GNG2GNB1
SCHEMBL1183589 0.75 MAPT (0.57) GSK3BPTPN1GNG2GNB1
SCHEMBL12620633 0.75 CYP3A4 (0.49) GSK3BPTPN1GNG2GNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014119617-A1 AMIDINE COMPOUND AND SALT THEREOF 富山化学工業株式会社 (JP) 2014-08-07 WO disclosed