Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.42 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15457426 | 0.86 | SMN1; SMN2 (0.35) | IDO1MAPTTAAR1HTTSMN1; SMN2 | |
| SCHEMBL3773680 | 0.83 | IDO1 (0.61) | IDO1MAPTTAAR1HTTNOS1 | |
| SCHEMBL22275783 | 0.80 | MAPT (0.67) | IDO1MAPTTAAR1HTTNOS1 | |
| Bromide SCHEMBL22263193 | 0.79 | MAPT (0.65) | IDO1MAPTTAAR1HTTNOS1 | |
| SCHEMBL3777472 | 0.79 | MAPT (0.65) | IDO1MAPTTAAR1HTTNOS1 | |
| SCHEMBL13007589 | 0.78 | IDO1 (0.57) | IDO1MAPTTAAR1HTTNOS1 | |
| Bromide SCHEMBL17260892 | 0.76 | IDO1 (0.56) | IDO1MAPTTAAR1HTTNOS1 | |
| SCHEMBL19499684 | 0.76 | MAPT (0.65) | IDO1MAPTTAAR1HTTNOS1 | |
| SCHEMBL14099906 | 0.75 | SMN1; SMN2 (0.43) | IDO1SMN1; SMN2 | |
| SCHEMBL14224743 | 0.73 | SMN1; SMN2 (0.42) | IDO1TAAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656953-B2 | Inhibition of cell proliferation | UNIVERSITY OF SOUTH FLORIDA (US) | 2017-05-23 | — | — | US | disclosed |
| US-20140221658-A1 | INHIBITION OF CELL PROLIFERATION | UNIVERSITY OF SOUTH FLORIDA (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221658-A1 | INHIBITION OF CELL PROLIFERATION | RB1, RAF1, NRAS | IDO1 4187/4885MAPT 3541/4885TAAR1 4545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.