Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | IDO1 | P14902 | 9/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.51 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.51 |
| ▸ | NOS1 | P29475 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ATP1A1 | P05023 | 1/20 | 0.45 |
| ▸ | ATP1B1 | P05026 | 1/20 | 0.45 |
| ▸ | ATP1A3 | P13637 | 1/20 | 0.45 |
| ▸ | ATP1B2 | P14415 | 1/20 | 0.45 |
| ▸ | ATP1A2 | P50993 | 1/20 | 0.45 |
| ▸ | ATP1B3 | P54709 | 1/20 | 0.45 |
| ▸ | FXYD2 | P54710 | 1/20 | 0.45 |
| ▸ | ATP1A4 | Q13733 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22275783 | 0.87 | MAPT (0.67) | MAPTIDO1TAAR1HTTSLC11A2 | |
| Bromide SCHEMBL22263193 | 0.86 | MAPT (0.65) | MAPTIDO1TAAR1HTTSLC11A2 | |
| SCHEMBL19499684 | 0.86 | MAPT (0.65) | MAPTIDO1TAAR1HTTSLC11A2 | |
| SCHEMBL29262559 | 0.82 | LMNA (0.50) | MAPTIDO1TAAR1LMNASMN1; SMN2 | |
| SCHEMBL3684816 | 0.81 | MAPT (0.74) | MAPTIDO1TAAR1HTTSLC11A2 | |
| Hydrochloric Acid SCHEMBL4008343 | 0.79 | MAPT (0.71) | MAPTIDO1TAAR1HTTSLC11A2 | |
| SCHEMBL15928217 | 0.79 | IDO1 (0.51) | MAPTIDO1TAAR1HTTSLC11A2 | |
| SCHEMBL11444341 | 0.78 | LMNA (0.40) | MAPTTAAR1LMNANPSR1 | |
| SCHEMBL3694691 | 0.77 | TAAR1 (0.50) | MAPTIDO1TAAR1HTTSLC11A2 | |
| Bromide SCHEMBL4448449 | 0.76 | TAAR1 (0.49) | MAPTIDO1TAAR1HTTSLC11A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | claimed |
| US-20060241185-A1 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-10-26 | — | — | US | claimed |
| US-7855228-B2 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STAMFORD JUNIOR UNIVERSITY (US) | 2010-12-21 | — | — | US | disclosed |
| WO-2007075177-A2 | ANTIBIOTICS TARGETING MREB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2007-07-05 | — | — | WO | disclosed |
| US-20060241185-A1 | Antibiotics targeting MreB | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241185-A1 | Antibiotics targeting MreB | SMC4, INCENP, DDB1 | MAPT 2901/4885IDO1 2985/4885TAAR1 4402/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.