Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | CASP2 | P42575 | 1/20 | 0.62 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15858238 | 0.92 | TDP1 (0.63) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL12530392 | 0.91 | TDP1 (0.51) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL5267898 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL20542891 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL31248065 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL23016672 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL12160128 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL20542889 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL13019126 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 | |
| SCHEMBL14190787 | 0.90 | TDP1 (0.61) | TDP1CASP2MAOAMAOBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221282-A1 | LONG DURATION DUAL HORMONE CONJUGATES | ASTRAZENECA PHARMACEUTICALS LP | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221282-A1 | LONG DURATION DUAL HORMONE CONJUGATES | SHBG, GHRHR, GNRHR | TDP1 4693/4885CASP2 3723/4885MAOA 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.