SCHEMBL15933152

SCHEMBL15933152

Cc1ccc(-c2ccc(-c3ccc(-c4cc(F)c(C(F)(F)Oc5cc(F)c(F)c(F)c5)c(F)c4)c(F)c3)cc2)cc1

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 1/20 0.34
FEN1 P39748 1/20 0.34
PDK2 Q15119 1/20 0.34
PDE3B Q13370 1/20 0.33
PDE3A Q14432 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
CYP1A2 P05177 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C19 P33261 1/20 0.32
PTGS2 P35354 1/20 0.32
RPS6KA3 P51812 1/20 0.32
AR P10275 1/20 0.31
ERN1 O75460 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
CYP11B1 P15538 2/20 0.31
CYP11B2 P19099 2/20 0.31
GPR3 P46089 1/20 0.31
GRM2 Q14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2741563 1.00 ALOX5AP (0.34) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL12625439 0.99 ALOX5AP (0.36) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL12624690 0.96 ALOX5AP (0.39) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL17951017 0.96 PDE3B (0.34) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL12814531 0.95 ALOX5AP (0.38) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL14767335 0.94 ALOX5AP (0.39) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL15374870 0.94 ALOX5AP (0.39) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL17951018 0.92 ALOX5AP (0.40) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL10259805 0.92 ALOX5AP (0.34) ALOX5APFEN1PDK2PDE3BPDE3A
SCHEMBL13447418 0.92 ALOX5AP (0.34) ALOX5APFEN1PDK2PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667840-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
US-11667840-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2023-06-06 US disclosed
US-10676670-B2 Liquid-crystalline medium and high-frequency components comprising same MERCK PATENT GMBH (DE) 2020-06-09 US disclosed
US-20190330530-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-10-31 US disclosed
US-20170349827-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2017-12-07 US disclosed
US-20170306230-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2017-10-26 US disclosed
WO-2016107671-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2016-07-07 WO disclosed
US-20140217325-A1 LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME MERCK PATENT GMBH (DE) 2014-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667840-B2 Liquid-crystalline medium FES, BLM, CXCL12 ALOX5AP 3593/4885FEN1 4028/4885PDK2 1419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.