Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15374870 | 1.00 | ALOX5AP (0.39) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL12814531 | 0.99 | ALOX5AP (0.38) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL17951018 | 0.99 | ALOX5AP (0.40) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL12624690 | 0.97 | ALOX5AP (0.39) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL2741563 | 0.94 | ALOX5AP (0.34) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL15933152 | 0.94 | ALOX5AP (0.34) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL14235285 | 0.94 | ALOX5AP (0.39) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL11891864 | 0.92 | ALOX5AP (0.39) | ALOX5APFEN1GPR3GRM2ERN1 | |
| SCHEMBL17951017 | 0.92 | PDE3B (0.34) | ALOX5APFEN1GRM2PDE3BPDE3A | |
| SCHEMBL12625439 | 0.92 | ALOX5AP (0.36) | ALOX5APFEN1GPR3ERN1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10982149-B2 | Chiral compounds | MERCK PATENT GMBH (DE) | 2021-04-20 | — | — | US | disclosed |
| US-10450509-B2 | Liquid crystal medium and liquid display | MERCK PATENT GMBH (DE) | 2019-10-22 | — | — | US | disclosed |
| US-20180223189-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-20180223189-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2018-08-09 | — | — | US | disclosed |
| US-9938464-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2018-04-10 | — | — | US | disclosed |
| US-9822305-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-21 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-9809749-B2 | Mesogenic compound, liquid-crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2017-11-07 | — | — | US | disclosed |
| US-20170226422-A1 | POLYMERISABLE MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2017-08-10 | — | — | US | disclosed |
| US-20170002290-A1 | ELECTRO-RHEOLOGICAL FLUID AND HAPTIC DEVICE | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2016-04-28 | — | — | US | disclosed |
| US-20150299572-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2015-10-22 | — | — | US | disclosed |
| US-20150247089-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-09-03 | — | — | US | disclosed |
| US-20150129800-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2015-05-14 | — | — | US | disclosed |
| WO-2014169985-A1 | MESOGENIC COMPOUND, LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-10-23 | — | — | WO | disclosed |
| US-20140225035-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-08-14 | — | — | US | disclosed |
| US-20140158934-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2014-06-12 | — | — | US | disclosed |
| WO-2014082699-A1 | LENS ELEMENT | MERCK PATENT GMBH (DE) | 2014-06-05 | — | — | WO | disclosed |
| US-8659737-B2 | Liquid crystal medium and liquid crystal display | MERCK PATENT GMBH (DE) | 2014-02-25 | — | — | US | disclosed |
| EP-2568032-A2 | Liquid crystal medium and liquid crystal display | Merck Patent GmbH (DE) | 2013-03-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10982149-B2 | Chiral compounds | FANCI, COL1A1, LCP1 | ALOX5AP 3674/4885FEN1 372/4885GPR3 2116/4885 |
| US-10450509-B2 | Liquid crystal medium and liquid display | NEFM, CRY1, BMP2 | ALOX5AP 3740/4885FEN1 3103/4885GPR3 3519/4885 |
| US-20160115388-A1 | MESOGENIC COMPOUND, LIQUID-CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | BMP2, IK, EML4 | ALOX5AP 3965/4885FEN1 4451/4885GPR3 3750/4885 |
| US-20150129800-A1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY | CCND2, CFD, CRY1 | ALOX5AP 2885/4885FEN1 4353/4885GPR3 3316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.