Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933152 | 1.00 | ALOX5AP (0.34) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL12625439 | 0.99 | ALOX5AP (0.36) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL12624690 | 0.96 | ALOX5AP (0.39) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL17951017 | 0.96 | PDE3B (0.34) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL12814531 | 0.95 | ALOX5AP (0.38) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL14767335 | 0.94 | ALOX5AP (0.39) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL15374870 | 0.94 | ALOX5AP (0.39) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL17951018 | 0.92 | ALOX5AP (0.40) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL10259805 | 0.92 | ALOX5AP (0.34) | ALOX5APFEN1PDK2PDE3BPDE3A | |
| SCHEMBL13447418 | 0.92 | ALOX5AP (0.34) | ALOX5APFEN1PDK2PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 419 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12043782-B2 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-12043781-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2024-07-23 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| US-11834599-B2 | Aromatic isothiocyanates | MERCK PATENT GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-20230383186-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-11-30 | — | — | US | disclosed |
| US-11788009-B2 | Liquid-crystalline medium for use in a switching element | MERCK PATENT GMBH (DE) | 2023-10-17 | — | — | US | disclosed |
| US-20230323209-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-10-12 | — | — | US | disclosed |
| US-20230313043-A1 | OPTICAL COMPONENT | MERCK PATENT GMBH (DE) | 2023-10-05 | — | — | US | disclosed |
| US-20100301270-A1 | LIQUID-CRYSTALLINE MEDUIM | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | US | disclosed |
| US-20100224827-A1 | LIQUID-CRYSTALLINE MEDIUM | WITTEK MICHAEL | 2010-09-09 | — | — | US | disclosed |
| US-20100219375-A1 | LIQUID-CRYSTALLINE MEDIUM | WITTEK MICHAEL | 2010-09-02 | — | — | US | disclosed |
| US-7763329-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-07-27 | — | — | US | disclosed |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | MERCK KGAA (DE) | 2010-07-22 | — | — | US | disclosed |
| WO-2010022891-A1 | LIQUID CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 2010-03-04 | — | — | WO | disclosed |
| US-20090289223-A1 | LIQUID-CRYSTALLINE MEDIUM | WITTEK MICHAEL | 2009-11-26 | — | — | US | disclosed |
| US-7595101-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2009-09-29 | — | — | US | disclosed |
| WO-2009033564-A2 | ELECTRO-OPTICAL LIGHT CONTROL ELEMENT, ELECTRO-OPTICAL DISPLAY AND CONTROL MEDIUM | MERCK PATENT GMBH (DE) | 2009-03-19 | — | — | WO | disclosed |
| US-20080083904-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-04-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | ALOX5AP 4739/4885FEN1 4188/4885PDK2 4357/4885 |
| US-20080083904-A1 | LIQUID-CRYSTALLINE MEDIUM | NEFM, OSBP, ALPG | ALOX5AP 4608/4885FEN1 3821/4885PDK2 2955/4885 |
| US-20100181533-A1 | Liquid-crystal compounds and LC media | VCL, LCT, NEFM | ALOX5AP 361/4885FEN1 4446/4885PDK2 2122/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.