SCHEMBL15933356

SCHEMBL15933356

Cc1cccc(C2C=CC=CC2O)c1C

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 5/20 0.40
TRPA1 O75762 1/20 0.38
ATM Q13315 1/20 0.38
HTR2A P28223 1/20 0.37
HTR2B P41595 1/20 0.37
ALDH1A1 P00352 1/20 0.32
PBRM1 Q86U86 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24385162 0.79 HTR2C (0.41) HTR2CTRPA1ATMHTR2AHTR2B
SCHEMBL15451802 0.78 HTR2C (0.40) HTR2CTRPA1ATMHTR2AHTR2B
SCHEMBL114449 0.74 HTR2C (0.46) HTR2CTRPA1ATMHTR2AHTR2B
SCHEMBL8907307 0.71 MAPT (0.36) HTR2CHTR2AHTR2BALDH1A1
SCHEMBL18477663 0.64 HTR2C (0.38) HTR2CHTR2AHTR2BALDH1A1PBRM1
SCHEMBL16956125 0.63 HTR2C (0.74) HTR2CTRPA1ATMHTR2AHTR2B
SCHEMBL23873432 0.63 HTR2C (0.51) HTR2CHTR2AHTR2BALDH1A1
SCHEMBL12993107 0.62 DHODH (0.32) HTR2CHTR2AHTR2B
Nitrogen SCHEMBL3316347 0.62 TRPA1 (0.55) TRPA1ATMALDH1A1
Water SCHEMBL29282906 0.62 TRPA1 (0.55) TRPA1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8946984-B2 Electroluminescent device BASF SE (DE) 2015-02-03 US disclosed
US-20140217335-A1 Electroluminescent Device BASF SE (DE) 2014-08-07 US disclosed