SCHEMBL24385162

SCHEMBL24385162

Cc1cccc(C2C=CC=CC2C)c1C

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTR2C P28335 7/20 0.41
HTR2A P28223 1/20 0.38
HTR2B P41595 1/20 0.38
TRPA1 O75762 1/20 0.34
ATM Q13315 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
KMT2A Q03164 1/20 0.33
PBRM1 Q86U86 1/20 0.32
DDB1 Q16531 1/20 0.30
CRBN Q96SW2 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18477663 0.86 HTR2C (0.38) HTR2CHTR2AHTR2BMEN1ALDH1A1
SCHEMBL15451802 0.79 HTR2C (0.40) HTR2CHTR2AHTR2BTRPA1ATM
SCHEMBL15933356 0.79 HTR2C (0.40) HTR2CHTR2AHTR2BTRPA1ATM
SCHEMBL114449 0.75 HTR2C (0.46) HTR2CHTR2AHTR2BTRPA1ATM
SCHEMBL28239632 0.71 SMN1; SMN2 (0.38) HTR2CHTR2AHTR2BMEN1ALDH1A1
SCHEMBL22086312 0.71 CYP3A4 (0.35) MEN1ALDH1A1KMT2A
SCHEMBL18656142 0.68 CYP3A4 (0.39) HTR2CHTR2AHTR2BMEN1KMT2A
SCHEMBL3429458 0.67 CYP11B2 (0.39) MEN1ALDH1A1KMT2ACYP2A6
SCHEMBL25060064 0.66 PBRM1 (0.34) ALDH1A1PBRM1
SCHEMBL28036409 0.66 CYP2C19 (0.42) HTR2CMEN1KMT2ACYP1A2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3992200-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2022-05-04 EP disclosed