Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 8/20 | 0.47 |
| ▸ | CRHR1 | P34998 | 10/20 | 0.46 |
| ▸ | GRM8 | O00222 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594404 | 0.91 | NPY1R (0.49) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1593938 | 0.90 | NPY1R (0.46) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL7043850 | 0.90 | ALDH1A1 (0.45) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1594245 | 0.89 | NPY1R (0.47) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL6520712 | 0.86 | NPY1R (0.49) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1593564 | 0.86 | CYP1A2 (0.48) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL6457651 | 0.86 | NPY1R (0.42) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1593495 | 0.85 | NPY1R (0.52) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1594081 | 0.83 | NPY1R (0.45) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1593270 | 0.81 | NPY1R (0.56) | NPY1RCRHR1GRM8CYP1A2GRM7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919329-B2 | Using proopiomelanocortin neuronal regulatory sequences to identify agents that affects caloric intake, energy expenditure, appetite or food intake; treating eating disorders and/or cachexia | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2011-04-05 | — | — | US | disclosed |
| US-7459432-B2 | Modification of feeding behavior | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 2008-12-02 | — | — | US | disclosed |
| US-20080213803-A1 | ASSESSMENT OF NEURONS IN THE ARCUATE NUCLEUS TO SCREEN FOR AGENTS THAT MODIFY FEEDING BEHAVIOR | OREGON HEALTH & SCIENCE UNIVERSITY | 2008-09-04 | — | — | US | disclosed |