Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 6/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRM8 | O00222 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043850 | 0.93 | ALDH1A1 (0.45) | NPY1RCRHR1ALDH1A1HPGDKDM4E | |
| SCHEMBL1593501 | 0.86 | NPY1R (0.47) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1594404 | 0.84 | NPY1R (0.49) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL7046358 | 0.84 | ALDH1A1 (0.47) | CRHR1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL1594245 | 0.82 | NPY1R (0.47) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1593296 | 0.81 | CRHR1 (0.48) | NPY1RCRHR1 | |
| SCHEMBL6520712 | 0.79 | NPY1R (0.49) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1593564 | 0.79 | CYP1A2 (0.48) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1593938 | 0.78 | NPY1R (0.46) | NPY1RCRHR1GRM8CYP1A2GRM7 | |
| SCHEMBL1594011 | 0.78 | NPY1R (0.68) | NPY1RCRHR1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1499277-A4 | MODIFICATION OF FEEDING BEHAVIOR | IMP COLLEGE INNOVATIONS LTD (GB) | 2005-08-31 | — | — | EP | disclosed |
| EP-1499277-A2 | MODIFICATION OF FEEDING BEHAVIOR | Imperial College Innovations Limited (GB) | 2005-01-26 | — | — | EP | disclosed |
| WO-2003026591-A2 | MODIFICATION OF FEEDING BEHAVIOR | IMPERIAL COLLEGE INNOVATIONS LTD. (GB) | 2003-04-03 | — | — | WO | disclosed |