SCHEMBL15935120

SCHEMBL15935120

COc1ccc(Nc2ccc3c(O)c(N=Nc4cc(C)c(N=Nc5ccc(N=Nc6cc(C)c(N=Nc7cc8c(S(=O)(=O)O)cccc8cc7S(=O)(=O)O)cc6OC)c(C)c5)cc4C)ccc3c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 9/20 0.53
MEN1 O00255 2/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KMT2A Q03164 2/20 0.41
CARM1 Q86X55 1/20 0.40
PRMT1 Q99873 1/20 0.40
PTPN1 P18031 2/20 0.39
CD40 P25942 1/20 0.37
CD40LG P29965 1/20 0.37
ATIC P31939 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HIF1A Q16665 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
CTRB1 P17538 1/20 0.36
PHLPP2 Q6ZVD8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17280503 1.00 ENPP2 (0.53) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL15935104 0.96 ENPP2 (0.47) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL15935123 0.96 ENPP2 (0.56) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL15935112 0.96 ENPP2 (0.56) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL17460855 0.95 ENPP2 (0.59) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL15935106 0.95 ENPP2 (0.47) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL19958058 0.94 ENPP2 (0.47) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL15935132 0.92 ENPP2 (0.50) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL15385564 0.91 ENPP2 (0.55) ENPP2MEN1NPC1RAB9AKMT2A
SCHEMBL15385573 0.91 ENPP2 (0.55) ENPP2MEN1NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 US disclosed
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 ENPP2 2889/4885MEN1 1701/4885NPC1 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.