Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474043 | 0.91 | APLNR (0.43) | PKMHSD17B10APLNRPOLBMEN1 | |
| SCHEMBL12431134 | 0.82 | HSD17B10 (0.48) | HSD17B10APLNRPOLBIDO1ADRA1A | |
| SCHEMBL11825653 | 0.80 | IDO1 (0.56) | HSD17B10APLNRIDO1ADRA1ATAAR1 | |
| SCHEMBL30861233 | 0.80 | IDO1 (0.56) | HSD17B10APLNRIDO1ADRA1ATAAR1 | |
| SCHEMBL1237862 | 0.80 | TSHR (0.41) | PKMHSD17B10APLNRPOLBMEN1 | |
| SCHEMBL29175430 | 0.80 | APLNR (0.41) | PKMHSD17B10APLNRPOLBMEN1 | |
| SCHEMBL16480388 | 0.80 | HSD17B10 (0.41) | PKMHSD17B10APLNRPOLBMEN1 | |
| SCHEMBL1237860 | 0.80 | APLNR (0.58) | APLNRMAPTIDO1ADRA1ATAAR1 | |
| SCHEMBL622035 | 0.79 | CHRM2 (0.47) | PKMMEN1LMNAMAPTKMT2A | |
| SCHEMBL1488919 | 0.79 | NPC1 (0.43) | HSD17B10APLNRPOLBMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014119770-A1 | PYRIDAZINONE COMPOUND AND HERBICIDE COMPRISING SAME | 住友化学株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |