SCHEMBL15935786

SCHEMBL15935786

COc1ccc(Nc2ccc3c(O)c(N=Nc4cc(C)c(N=Nc5cc(C)c(N=Nc6cc(C)c(N=Nc7cc8c(S(=O)(=O)O)cc(S(=O)(=O)O)cc8cc7S(=O)(=O)O)cc6OC)cc5C)cc4C)c(S(=O)(=O)O)cc3c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 11/20 0.71
CARM1 Q86X55 1/20 0.46
PRMT1 Q99873 1/20 0.46
CD40 P25942 1/20 0.46
CD40LG P29965 1/20 0.46
PHLPP2 Q6ZVD8 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HIF1A Q16665 1/20 0.44
PTPN1 P18031 2/20 0.44
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935776 1.00 ENPP2 (0.71) ENPP2CARM1PRMT1CD40CD40LG
SCHEMBL19958244 0.97 ENPP2 (0.70) ENPP2CARM1PRMT1CD40CD40LG
SCHEMBL15935792 0.96 ENPP2 (0.65) ENPP2CARM1PRMT1CD40CD40LG
SCHEMBL15935775 0.96 ENPP2 (0.66) ENPP2CARM1PRMT1CD40CD40LG
SCHEMBL17284053 0.96 ENPP2 (0.66) ENPP2CARM1PRMT1CD40CD40LG
SCHEMBL19235100 0.94 ENPP2 (0.63) ENPP2CARM1PRMT1CD40CD40LG
SCHEMBL17283952 0.94 ENPP2 (0.81) ENPP2PRMT1CD40CD40LGPHLPP2
SCHEMBL14773714 0.94 ENPP2 (0.81) ENPP2PRMT1CD40CD40LGPHLPP2
SCHEMBL19958178 0.94 ENPP2 (0.81) ENPP2PRMT1CD40CD40LGPHLPP2
SCHEMBL19234841 0.94 ENPP2 (0.81) ENPP2PRMT1CD40CD40LGPHLPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 US disclosed
WO-2017135391-A1 POLARIZER ELEMENT, AND POLARIZING PLATE AND DISPLAY DEVICE USING SAME 日本化薬株式会社 2017-08-10 WO disclosed
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 ENPP2 2889/4885CARM1 1634/4885PRMT1 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.