Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2728818 | 1.00 | USP2 (0.53) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL30477515 | 1.00 | USP2 (0.53) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL5834397 | 1.00 | USP2 (0.53) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL6435202 | 0.98 | USP2 (0.50) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL27615327 | 0.91 | TSHR (0.42) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL565662 | 0.91 | — | — | |
| SCHEMBL3433294 | 0.89 | ALDH1A1 (0.63) | ALDH1A1CNR1CNR2MAPTMEN1 | |
| SCHEMBL14374273 | 0.89 | ALDH1A1 (0.63) | ALDH1A1CNR1CNR2MAPTMEN1 | |
| Iodide SCHEMBL27860357 | 0.88 | TSHR (0.41) | USP2DNM1ALDH1A1CNR1CNR2 | |
| SCHEMBL28831490 | 0.88 | HTT (0.59) | USP2HTTMAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118556-A2 | SELECTIVE INHIBITORS AND ALLOSTERIC ACTIVATORS OF SPHINGOSINE KINASE | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2014-08-07 | — | — | WO | disclosed |