Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15936275 | 0.88 | KDM4E (0.40) | SQORGAAKDM4ESMN1; SMN2GLA | |
| SCHEMBL2822812 | 0.84 | IKBKB (0.40) | IKBKBSQORRAB9AGAAPRKCZ | |
| SCHEMBL2822703 | 0.73 | MET (0.48) | IKBKBRAB9APRKCZKDM4ESMN1; SMN2 | |
| SCHEMBL2816872 | 0.71 | SQOR (0.41) | SQORGAAKDM4ESMN1; SMN2GLA | |
| SCHEMBL2819107 | 0.70 | GAA (0.46) | IKBKBSQORRAB9AGAAPRKCZ | |
| SCHEMBL2816429 | 0.69 | SQOR (0.51) | IKBKBSQORGAAKDM4ESMN1; SMN2 | |
| SCHEMBL2818501 | 0.67 | IKBKB (0.38) | IKBKBSQORRAB9AGAAPRKCZ | |
| SCHEMBL16423665 | 0.66 | CYP2C19 (0.62) | RAB9AGAAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL2819321 | 0.65 | MET (0.52) | IKBKBRAB9AGAAPRKCZKDM4E | |
| SCHEMBL2816056 | 0.65 | IKBKB (0.47) | IKBKBSQORRAB9AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2061790-B1 | Substituted aminopyrazolopyridines and salts thereof, their preparations and pharmaceutical compositions comprising them | BAYER IP GMBH (DE) | 2014-08-13 | — | — | EP | disclosed |