Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.57 |
| ▸ | FFAR1 | O14842 | 12/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508056 | 0.86 | FFAR1 (0.48) | MRGPRX4FFAR1FFAR4MMP2MMP9 | |
| SCHEMBL6205346 | 0.78 | CHRM2 (0.53) | MRGPRX4FFAR1 | |
| SCHEMBL13462733 | 0.78 | MRGPRX4 (0.58) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL1745369 | 0.76 | FFAR1 (0.76) | FFAR1FFAR4AKR1B1 | |
| SCHEMBL5636 | 0.76 | MMP2 (0.56) | MRGPRX4FFAR1FFAR4MMP2MMP9 | |
| SCHEMBL5635 | 0.76 | MMP2 (0.51) | MRGPRX4FFAR1FFAR4MMP2MMP9 | |
| SCHEMBL13439807 | 0.76 | MRGPRX4 (0.55) | MRGPRX4MMP2MMP9MMP14ADAM17 | |
| SCHEMBL15936281 | 0.76 | MRGPRX4 (0.57) | MRGPRX4FFAR1MMP2MMP9MMP14 | |
| SCHEMBL1744720 | 0.75 | FFAR1 (0.53) | MRGPRX4FFAR1FFAR4MMP2MMP9 | |
| SCHEMBL3375496 | 0.75 | MRGPRX4 (0.62) | MRGPRX4FFAR1MMP2MMP9MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289868-B1 | CARBOXYLIC ACID COMPOUND | DAIICHI SANKYO CO LTD (JP) | 2014-08-13 | — | — | EP | disclosed |