Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5810 | 0.90 | MMP1 (0.48) | MMP2MMP9MMP14ADAM17MRGPRX4 | |
| SCHEMBL6211 | 0.81 | MAOB (0.57) | MMP2MMP9ADAM17FFAR1MAOB | |
| SCHEMBL5637 | 0.79 | MMP2 (0.50) | MMP2MMP9MMP14ADAM17MRGPRX4 | |
| SCHEMBL6157 | 0.77 | PARP10 (0.43) | FFAR1 | |
| SCHEMBL11898792 | 0.77 | ADAMTS4 (0.48) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11899992 | 0.77 | PARP10 (0.48) | FFAR1 | |
| SCHEMBL5796 | 0.76 | MAOB (0.46) | ADAM17FFAR1MAOB | |
| SCHEMBL5636 | 0.76 | MMP2 (0.56) | MMP2MMP9MMP14ADAM17MRGPRX4 | |
| SCHEMBL15936282 | 0.76 | MRGPRX4 (0.57) | MMP2MMP9MMP14ADAM17MRGPRX4 | |
| SCHEMBL13462733 | 0.74 | MRGPRX4 (0.58) | MMP2MMP9MMP14ADAM17MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488489-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | Pfizer Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011045703-A2 | C-LINKED HYDROXAMIC ACID DERIVATIVES USEFUL AS ANTIBACTERIAL AGENTS | PFIZER INC. (US) | 2011-04-21 | — | — | WO | disclosed |