Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | GGT1 | P19440 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL20267044 | 0.86 | TSHR (0.52) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Aniline SCHEMBL7175507 | 0.85 | TSHR (0.65) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Aniline SCHEMBL1956601 | 0.85 | TSHR (0.65) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Aniline SCHEMBL25370313 | 0.85 | TSHR (0.65) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Aniline SCHEMBL30678504 | 0.85 | TSHR (0.65) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Aniline SCHEMBL27343211 | 0.84 | TSHR (0.50) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Biphenyl SCHEMBL5748779 | 0.83 | SMN1; SMN2 (0.54) | TSHRALDH1A1HSD17B10TDP1NAPRT | |
| Aniline SCHEMBL28431695 | 0.82 | TSHR (0.61) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Aniline SCHEMBL27419313 | 0.82 | TSHR (0.61) | TSHRALDH1A1PBRM1HSD17B10TDP1 | |
| Aniline SCHEMBL27815330 | 0.82 | TSHR (0.61) | TSHRALDH1A1PBRM1HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745022-B1 | HISTONE DEACETYLASE INHIBITOR PRODRUGS | ATON PHARMA INC (US) | 2014-08-13 | — | — | EP | claimed |