Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.44 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.44 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6223235 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2MAPTBACE1ALDH1A1CYP1A2 | |
| Aniline SCHEMBL15936366 | 0.83 | TSHR (0.52) | MAPTALDH1A1GAACYP2C19PTGS2 | |
| Biphenyl SCHEMBL27819830 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTBACE1ALDH1A1CYP2C19 | |
| Biphenyl SCHEMBL6269566 | 0.82 | MAPT (0.56) | SMN1; SMN2MAPTBACE1ALDH1A1CYP1A2 | |
| Biphenyl SCHEMBL8773175 | 0.82 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTBACE1ALDH1A1CYP1A2 | |
| Biphenyl SCHEMBL2670012 | 0.81 | MAPT (0.61) | SMN1; SMN2MAPTALDH1A1GAACYP2C19 | |
| Biphenyl SCHEMBL27766330 | 0.81 | SMN1; SMN2 (0.61) | SMN1; SMN2MAPTALDH1A1GAAPTGS2 | |
| Biphenyl SCHEMBL1822628 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTALDH1A1GAACYP2C9 | |
| Benzene SCHEMBL4654902 | 0.81 | FFAR3 (0.47) | MAPTALDH1A1GAAPTGS2TDP1 | |
| Biphenyl SCHEMBL29059196 | 0.81 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTALDH1A1GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109568300-A | Felbinac or its salt are preparing the application in Xa inhibitor medicaments | 石家庄以岭药业股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-106983718-B | A kind of preparation method of felbinac or its tromethamine saline injection | 广东中科药物研究有限公司 | 2019-01-11 | — | — | CN | claimed |
| CN-106983718-A | A kind of preparation method of felbinac or its tromethamine saline injection | 广东中科药物研究有限公司 | 2017-07-28 | — | — | CN | claimed |
| CN-105769758-A | Felbinac salt eye drops, as well as preparation method and application thereof | 广东中科药物研究有限公司 | 2016-07-20 | — | — | CN | claimed |
| CN-103169653-A | Biphenylacetic acid and novel use of biphenylacetate | GUANGDONG ZONK DRUG R & D LTD | 2013-06-26 | — | — | CN | claimed |
| CN-102885803-A | Application of felbinac tromethamine salt to preparation of medicine for treating eye inflammatory reactions | GUANGDONG ZONK DRUG R & D LTD | 2013-01-23 | — | — | CN | claimed |
| CN-101331112-B | Biphenyl acetate as well as preparation method and application thereof | GUANGDONG ZONK DRUG R & D LTD | 2012-03-21 | — | — | CN | claimed |
| CN-101168502-B | Biphenyl ammonia acetate butantriol salt and preparation method thereof | GUANGDONG ZONK DRUG R & D LTD | 2010-09-08 | — | — | CN | claimed |
| CN-101331112-A | Biphenyl acetate as well as preparation method and application thereof | GUANGDONG ZONK DRUG R & D LTD (CN) | 2008-12-24 | — | — | CN | claimed |
| CN-101168502-A | Biphenyl ammonia acetate butantriol salt and preparation method thereof | GUANGDONG ZONK DRUG R & D LTD (CN) | 2008-04-30 | — | — | CN | claimed |
| CN-101156841-A | An antineoplastic new use of biphenyl acetic acid and its salt | WENZHAN CHEN (CN) | 2008-04-09 | — | — | CN | claimed |
| CN-1944378-A | Biphenyl ammonia acetate butantriol salt and its preparing method | ZHONGKE MEDICINE RES CO LTD GU (CN) | 2007-04-11 | — | — | CN | claimed |
| CN-110290781-A | The dosage form of stomach and intestine privileged site control release | 南京三迭纪医药科技有限公司 | 2019-09-27 | — | — | CN | disclosed |
| CN-107847398-B | Control the pharmaceutical dosage form of release | 南京三迭纪医药科技有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-109568300-A | Felbinac or its salt are preparing the application in Xa inhibitor medicaments | 石家庄以岭药业股份有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-109432039-A | Pharmaceutical formulation and its use | 南京三迭纪医药科技有限公司 | 2019-03-08 | — | — | CN | disclosed |
| US-20050096335-A1 | Heteroaryl - fused nitrogen heterocycles as therapeutic agents | TRANSTECH PHARMA, INC. | 2005-05-05 | — | — | US | disclosed |
| EP-1438310-A1 | BETA-CARBOLIN DERIVATIVES AS PTP-INHIBITORS | TransTech Pharma Inc. (US) | 2004-07-21 | — | — | EP | disclosed |
| US-20040014778-A1 | Heteroaryl - fused nitrogen heterocycles as therapeutic agents | VTVX HOLDINGS I LLC | 2004-01-22 | — | — | US | disclosed |
| WO-2003033496-A1 | BETA-CARBOLIN DERIVATIVES AS PTP-INHIBITORS | TRANSTECH PHARMA, INC. (US) | 2003-04-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040014778-A1 | Heteroaryl - fused nitrogen heterocycles as therapeutic agents | PTPRG, PTPRM, PTPRC | SMN1; SMN2 3945/4885MAPT 770/4885BACE1 261/4885 |
| US-20050096335-A1 | Heteroaryl - fused nitrogen heterocycles as therapeutic agents | PTPRG, PTPRM, PTPRC | SMN1; SMN2 3945/4885MAPT 770/4885BACE1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.