Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 17/20 | 0.55 |
| ▸ | MMEL1 | Q495T6 | 7/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912589 | 0.82 | MME (0.82) | MMEMMEL1 | |
| SCHEMBL15986382 | 0.78 | MME (0.82) | MMEMMEL1 | |
| SCHEMBL1912664 | 0.76 | MME (0.85) | MMEMMEL1 | |
| SCHEMBL2874674 | 0.75 | MME (0.83) | MMEMMEL1 | |
| SCHEMBL2874678 | 0.75 | MME (0.83) | MMEMMEL1 | |
| SCHEMBL10713766 | 0.74 | ACLY (0.53) | — | |
| SCHEMBL14959388 | 0.73 | MMEL1 (0.59) | MMEMMEL1 | |
| SCHEMBL15943037 | 0.72 | MME (0.82) | MMEMMEL1 | |
| SCHEMBL1912584 | 0.71 | MME (0.80) | MMEMMEL1 | |
| SCHEMBL2878301 | 0.71 | MME (0.80) | MMEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435409-B1 | SUBSTITUTED AMINOPROPIONIC DERIVATIVES AS NEPRILYSIN INHIBITORS | NOVARTIS AG (CH) | 2014-08-13 | — | — | EP | disclosed |