Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15932398 | 0.78 | NAMPT (0.55) | NAMPTKDM4EPKM | |
| SCHEMBL21088591 | 0.77 | NAMPT (0.62) | NAMPTKDM4EPKMACKR3RORC | |
| SCHEMBL5870674 | 0.75 | NAMPT (0.62) | NAMPTKDM4EPKMACKR3RORC | |
| SCHEMBL31033426 | 0.75 | NAMPT (0.50) | NAMPTKDM4EPKMACKR3RORC | |
| SCHEMBL31033427 | 0.75 | NAMPT (0.50) | NAMPTKDM4EPKMACKR3RORC | |
| SCHEMBL8651537 | 0.74 | NAMPT (0.61) | NAMPTKDM4EPKMACKR3RORC | |
| SCHEMBL3713202 | 0.74 | NAMPT (1.00) | NAMPTKDM4EPKMACKR3MAPK1 | |
| SCHEMBL15936742 | 0.74 | NAMPT (0.47) | NAMPTKDM4EPKM | |
| SCHEMBL30662885 | 0.73 | NAMPT (0.43) | NAMPTKDM4EPKMACKR3RORC | |
| SCHEMBL26610953 | 0.73 | NAMPT (0.43) | NAMPTKDM4EPKMACKR3RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | disclosed |