Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | ACACB | O00763 | 10/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15934192 | 0.77 | NAMPT (0.49) | NAMPTDRD2ACACBCKS1BSKP1 | |
| SCHEMBL21089377 | 0.76 | NAMPT (0.56) | NAMPTDRD2ACACBCKS1BSKP1 | |
| SCHEMBL25081005 | 0.74 | NAMPT (0.67) | NAMPTDRD2ACACBCKS1BSKP1 | |
| SCHEMBL16745437 | 0.74 | NAMPT (0.46) | NAMPTDRD2ACACBCKS1BSKP1 | |
| SCHEMBL15936729 | 0.74 | NAMPT (0.58) | NAMPTKDM4EPKM | |
| SCHEMBL25080814 | 0.72 | NAMPT (0.53) | NAMPTDRD2ACACBCKS1BSKP1 | |
| SCHEMBL21088591 | 0.72 | NAMPT (0.62) | NAMPTDRD2KDM4EPKM | |
| SCHEMBL3024605 | 0.71 | NAMPT (0.50) | NAMPTDRD2ACACBCKS1BSKP1 | |
| SCHEMBL7390125 | 0.70 | NAMPT (0.49) | NAMPTDRD2ACACBCKS1BSKP1 | |
| SCHEMBL15841222 | 0.70 | NAMPT (0.46) | NAMPTDRD2ACACBCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | disclosed |