Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31033426 | 1.00 | NAMPT (0.50) | NAMPTKDM1ANR1H2KDM4EPKM | |
| SCHEMBL28341502 | 0.82 | NAMPT (0.54) | NAMPTNR1H2KDM4EPKMRORC | |
| SCHEMBL21723072 | 0.82 | MGLL (0.51) | NAMPTNR1H2RORCGPR119USP30 | |
| SCHEMBL15684511 | 0.81 | KDM4E (0.51) | NAMPTKDM1AKDM4EPKMGPR119 | |
| SCHEMBL25471652 | 0.80 | PRMT5 (0.47) | NAMPTKDM1ANR1H2KDM4EPKM | |
| SCHEMBL18497375 | 0.77 | GPR119 (0.49) | NAMPTNR1H2KDM4EPKMGPR119 | |
| SCHEMBL27158359 | 0.75 | ACKR3 (0.50) | NAMPTKDM1AKDM4EPKMUSP30 | |
| SCHEMBL15845815 | 0.75 | KDM4E (0.51) | KDM1AKDM4EPKMGPR119 | |
| SCHEMBL23802337 | 0.75 | GPR119 (0.48) | NAMPTNR1H2KDM4EPKMGPR119 | |
| SCHEMBL23830741 | 0.75 | NAMPT (0.53) | NAMPTNR1H2KDM4EPKMRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024175905-A1 | DIMER COMPOUNDS | Kesmalea Therapeutics Limited (GB) | 2024-08-29 | — | — | WO | disclosed |